2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1099R
    Hycanthone (Standard)
    		Inhibitor
    Hycanthone (Standard) is the analytical standard of Hycanthone. This product is intended for research and analytical applications. Hycanthone is a thioxanthenone DNA intercalator and inhibits RNA synthesis as well as the DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits apurinic endonuclease-1 (APE1) by direct protein binding with a KD of 10 nM. Hycanthone is a bioactive metabolite of Lucanthone (HY-B2098) and has anti-schistosomal agent.
    Hycanthone (Standard)
  • HY-W079315
    5-Phenylthieno[2,3-d]pyrimidin-4-amine
    5-Phenylthieno[2,3-d]pyrimidin-4-amine (Compound 3b) is a heterocyclic compound with antiviral and antiprotozoal activities.
    5-Phenylthieno[2,3-d]pyrimidin-4-amine
  • HY-155401
    Antitrypanosomal agent 18
    		Inhibitor
    Antitrypanosomal agent 18 (compound 8b) is a nitrofuran derivative has strong trypanocidal activity in vitro with an IC50 value of 0.03 μM.
    Antitrypanosomal agent 18
  • HY-N12232
    Carbazomycin D
    		Inhibitor
    Carbazomycin D exhibits antituberculosis and antimalarial activities, that inhibits Plasmodium falciparum with an IC50 > 10 μg/mL, inhibits Mycobacterium tuberculosis with MIC of 25 μg/mL. Carbazomycin D exhibits cytotoxicity in cell MCF-7, KB, NCI-H187 and Vero, with IC50s of 21.3, 33.2, 12.9, and 34.3 μg/mL, respectively.
    Carbazomycin D
  • HY-175506
    RyRs activator 6
    		Inhibitor
    RyRs activator 6 (compound C3) is a ryanodine receptor (RyRs) activator that activates calcium release in insect neurons. RyRs activator 6 has insecticidal activity.
    RyRs activator 6
  • HY-163780
    AChE-IN-66
    		Inhibitor
    Nematicidal agent 1 is a potent nematicidal agent. Nematicidal agent 1 binds to the pocket of acetylcholine esterase (AChE).
    AChE-IN-66
  • HY-N0336R
    3-Butylidenephthalide (Standard)
    		Inhibitor
    3-Butylidenephthalide (Standard) is the analytical standard of 3-Butylidenephthalide. This product is intended for research and analytical applications. 3-Butylidenephthalide (Butylidenephthalide) is a phthalic anhydride derivative identified in Ligusticum chuanxiong Hort, and has larvicidal activity (LC50 of 1.56 mg/g for Spodoptera litura larvae).
    3-Butylidenephthalide (Standard)
  • HY-13832R
    Atovaquone (Standard)
    		Inhibitor
    Atovaquone (Standard) is the analytical standard of Atovaquone. This product is intended for research and analytical applications. Atovaquone (Atavaquone) is a potent, selective and orally active inhibitor of the parasite’s mitochondrial cytochrome bc1 complex. Atovaquone is against human and  P. falciparum cytochrome bc1 activity with IC50 values of 460 nM and 2.0 nM, respectively. Atovaquone is an antimalarial agent and has the potential for the investigation of neumocystis pneumonia, toxoplasmosis, malaria, and babesia.
    Atovaquone (Standard)
  • HY-N8484
    Eprinomectin B1b
    Eprinomectin B1b is a minor component and belongs to the avermectin family of insecticides and anthelmintics.
    Eprinomectin B1b
  • HY-W018025R
    5,6-Dihydroxyindole (Standard)
    		Inhibitor
    5,6-Dihydroxyindole (Standard) is the analytical standard of 5,6-Dihydroxyindole. This product is intended for research and analytical applications. 5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum antibacterial, antifungal, antiviral, antiparasitic activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens.
    5,6-Dihydroxyindole (Standard)
  • HY-174325
    Antimalarial agent 50
    		Inhibitor
    Antimalarial agent 50 is an antiplasmodial compound. Antimalarial agent 50 has an effect against Plasmodium berghei induced malaria infection in mice model. Antimalarial agent 50 can regulate oxidative stress and significantly reduce the levels of inflammatory factors. Antimalarial agent 50 can be used for the research of the malaria.
    Antimalarial agent 50
  • HY-N13288
    Cordysinin C/D
    		Inhibitor
    Cordysinin C/D (compound 9) is a potential anti-plasmodial compound that can effectively inhibit Plasmodium falciparum 3D7 strain.
    Cordysinin C/D
  • HY-N15187
    Acronycidine
    		Inhibitor
    Acronycidine is a quinoline alkaloid with antimalarial activity and can be extracted from Acronychia baueri Schott. Acronycidine can be utilized in malari research.
    Acronycidine
  • HY-B1953R
    Thiacloprid (Standard)
    		Inhibitor
    Thiacloprid (Standard) is the analytical standard of Thiacloprid. This product is intended for research and analytical applications. Thiacloprid, a chloronicotinyl insecticide, is targeted chiefly to control aphid pest species in orchards and vegetables. Thiacloprid destabilizes DNA. Thiacloprid changes the structure and stability of DNA through binding into the minor groove by hydrophobic or hydrogen interactions.
    Thiacloprid (Standard)
  • HY-W357413
    Chinifur
    		Inhibitor
    Chinifur (Quinifuryl), a Nitrofuran derivative, is a selective inhibitor of trypanothione reductase and also a radical-generating substrate for trypanothione reductase (Ki = 4.5 μM).
    Chinifur
  • HY-168069
    DHFR-IN-20
    		Inhibitor
    DHFR-IN-20 (Compound LA1) is a Plasmodium falciparum dihydrofolate reductase (DHFR) inhibitor, with Kis of 0.16, 0.30, 6.6 nM for PfDHFR-WT, PfDHFR-QM, HsDHFR. DHFR-IN-20 has antimalarial activities (IC50: 1.4 nM and 1.6 μM for P. falciparum carrying the wild-type (TM4/8.2) and the quadruple mutant (V1/S) PfDHFR enzyme.
    DHFR-IN-20
  • HY-N14068
    Cytosaminomycin B
    		Inhibitor
    Cytosaminomycin B has anti-Eimeria Tenella activity.
    Cytosaminomycin B
  • HY-N8374
    Pheanthine
    		Inhibitor
    Pheanthine (Compound 2) is an antiplasmodial agent, that inhibits chloroquine-resistant Plasmodium falciparum K-1 (IC50 is 0.8 μM) and chloroquine-sensitive P. falciparum strain NF54 A19A (IC50 of 0.03 μM). Pheanthine exhibits low cytotoxicity in human lung fibrosblast (MRC-5, IC50 is 11.2 μM) and macrophages (PMM, IC50 is 8 μM).
    Pheanthine
  • HY-175345
    CYP3A4-IN-5
    		Inhibitor
    CYP3A4-IN-5 (Compound 5p) is a potent Leishmania major pteridine reductase 1 (Lm PTR1) inhibitor (IC50=12.77 µM). CYP3A4-IN-5 is promising for research of parasite infection.
    CYP3A4-IN-5
  • HY-N14069
    Cytosaminomycin C
    		Inhibitor
    Cytosaminomycin C has anti-Eimeria Tenella activity.
    Cytosaminomycin C
Parasite Isoform Comparison

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